Our lab investigates the neural circuits and computations involved in reward learning and decision-making, and their potential alterations in neuropsychiatric disorders.
We use theory-driven behavioral tasks in rodents (inspired by formal learning theories), in combination with modern neuroscience tools to monitor and manipulate neural activity (e.g. fiber-photometry, optogenetics, chemogenetics). Our goal is to define the relevant information-processing principles (the general rules that govern behavior) and the underlying neural circuits dynamics. Brain circuits of interest include midbrain dopamine neurons and their neuromodulatory influence on striatal and prefrontal networks.